Four References Comparing Biodosimetry Assays
- Optimizing the use of biodosimetry tools in a mass casualty incident when surge with high throughput is necessary,
adapted from Sullivan JM et al., Assessment of Biodosimetry Methods for a Mass Casualty Radiological Incident: Medical Response and Management Considerations. Health Phys. 2013;105(6):540-554, See Table 1.
- Cytogenetic aberration assays used for dose assessment (PDF - 64 KB),
adapted from Cytogenetic Dosimetry: Applications in Preparedness for and Response to Radiation Emergencies, Table 1, page 3, (IAEA, PAHO, WHO, September 2011)
- Summary of advantages and disadvantages of existing and developing techniques for assessment of radiation exposure levels,
adapted from High dose radiation effects and tissue injury, Report of the Independent Advisory Group on Ionising Radiation, Table 4.4, page 41 (Health Protections Agency, UK, March 2009) (PDF - 865 KB)
- Comparison of retrospective dosimetry assays (PDF - 97 KB),
adapted from Ainsbury EA, Bakhanova E, Barquinero JF, et al., Review of retrospective dosimetry techniques for external ionising radiation exposure. Table 1, Radiat Prot Dosimetry. 2011;147(4):573-92. Epub 2010 Dec 23. [PubMed Citation]
- See REMM Biodosimetry Reference List
- Many of the newer biodosimetry techniques mentioned in the papers in the reference list could be considered when used by experts as supplemental data for clinical evaluation...
- If performed by experienced, reference laboratories using procedures that have been precisely calibrated for specific conditions
- But most are probably not FDA-certified for clinical use in evaluating radiation exposure
- But most are currently not feasible in large mass casualty events needing high throughput