Notes on the graphs above:
Source: Dicentric chromosome - Genetic Home Reference, (NIH/NLM)
- Radiation exposure causes DNA strand breaks leading to abnormal chromosome replication, including dicentric chromosome formation. This figure illustrates the double-strand break.
- Increases in radiation dose produce increasing numbers of aberrant (dicentric) chromosomes.
- The number of dicentric chromosomes correlates well with radiation dose (i.e., increases in dose produce increased numbers of dicentric chromosomes).