Acute Effects:
Blister, Moist Desquamation, Ulcer, Necrosis
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                        Clinical photo of blister and moist desquamation
Source: Turai I, Veress K, Gunalp B, Souchkevitch G. Medical response to radiation incidents and radionuclear threats. BMJ. 2004 Mar 6;328(7439):568-72. [PubMed Citation]

Clinical history: Acute skin blister and ulceration in a Peruvian patient 3 days after exposure. He inadvertently placed a 26-Ci (0.962-TBq) Iridium-192 source in his back pocket for 6.5 hours. At that time he complained of pain in his posterior right thigh. Eventually he developed massive ulceration and necrosis of the site with infection, and his right leg was eventually amputated.
Left photo: Blister with surrounding erythema 3 days after exposure
Right photo: Confluent moist desquamation with peripheral necrosis, 10 days after exposure
Bottom photo: Tissue necrosis: Evolution of previous lesion; large area of deep skin/dermal/connective tissue ulceration and necrosis. Amputation of extremity was eventually required.
Clinical photo of tissue necrosis
Source: Radiation Protection in Diagnostic and Interventional Radiology (PowerPoint - 2.07 MB) (IAEA)

Reference:
The radiological accident in Yanango (PDF - 3.30 MB) (IAEA, 2000)